Event Based PrEP

"The science supporting the efficacy of event-based PrEP has been around since 2008 and is commonly used in many European countries. With the World Health Organization (WHO) endorsing the protocol this past June, several agencies around the U.S. have begun to endorse the protocol as well. Through consultation with some of Utah’s foremost infectious disease clinicians working in HIV prevention, treatment, and care, the Utah AIDS Foundation is proud to be the first agency in Utah to openly endorse the efficacy of the ED-PrEP regimen. The science is there, and we will always strive to provide and advocate for high impact evidence-based tools that the communities we serve deserve. It is important to note that the on ED-PrEP protocol is currently not FDA approved and should be considered through consultation with your medical provider. To learn more about the protocol, we encourage you to visit our website, utahaids.org, and reference the WHO technical brief accessed at https://www.who.int/hiv/pub/prep/211/en/.

-Ahmer Afroz, MPH, CHES, Executive Director

What is event-driven PrEP?

Event-based PrEP (ED-PrEP), commonly referred to as on-demand PrEP or PrEP 2-1-1, is taking Truvada only around the time of sex or potential HIV transmission. This is instead of taking Truvada daily.

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Science behind ED- PrEP

There is a lot of research behind supporting ED-PrEP. We highly recommend those interested to review the World Health Organization (WHO) technical brief for a comprehensive overview of the research. The WHO technical brief can accessed from https://www.who.int/hiv/pub/prep/211/en/.

Who should consider ED-PrEP

Per World Health Organization guidance, ED-PrEP could be considered:

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Things to Consider

While PrEP failures are rare, they can occur. This is also true of the ED-PrEP protocol and we encourage all those interested to research their options and consult a medical provider before beginning the protocol.It is important to note that since this protocol is currently not FDA approved, some providers may refuse to endorse the 2-1-1 protocol. If you are having trouble finding an accommodating provider, please contact us for further assistance.